Postnatal amniotic fluid intake reduces gut inflammatory responses and 1 necrotizing enterocolitis in preterm neonates
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چکیده
Postnatal amniotic fluid intake reduces gut inflammatory responses and 1 necrotizing enterocolitis in preterm neonates 2 3 Jayda Siggers, Mette V. Østergaard, Richard H. Siggers, Kerstin Skovgaard, Lars Mølbak, 4 Thomas Thymann, Mette Schmidt, Hanne K. Møller, Stig Purup, Lisbeth N. Fink, Hanne 5 Frøkiær, Mette Boye, Per T. Sangild, Stine B. Bering 6 7 1 Department of Human Nutrition, Faculty Science, University of Copenhagen, Frederiksberg, 8 Denmark; 2 National Veterinary Institute, Technical University of Denmark, Copenhagen, 9 Denmark; 3 Department of Veterinary Reproduction, Faculty of Health and Medical Sciences, 10 University of Copenhagen, Frederiksberg, Denmark; Department of Systems Biology, Technical 11 University of Denmark, Lyngby, Denmark, Department of Animal Science, Aarhus University, 12 Tjele, Denmark. 13 14 Running head: Amniotic fluid and necrotizing enterocolitis in preterm neonates 15 16 Together, the authors contributed to study concept and design (JS, MVØ, RHS, TT, MS, PTS), 17 acquisition of data (JS, MVØ, RHS, KS, SBB, LM, HKM, SP, TT, MS, MB, PTS), data analysis 18 and interpretation (JS, MVØ, RHS, KS, SBB, LM, HKM, SP, TT, MS, LNF, HF, MB, PTS) and 19 manuscript preparation and critical comments (JS, MVØ, RHS, KS, SBB, HKM, HF, MB, PTS). 20 21 The work was supported by the Danish Research Councils and the Veterinary Institute, Technical 22 University of Denmark. 23 The authors have no conflicts of interest. 24 25 Corresponding author: 26 Articles in PresS. Am J Physiol Gastrointest Liver Physiol (March 21, 2013). doi:10.1152/ajpgi.00278.2012
منابع مشابه
Postnatal amniotic fluid intake reduces gut inflammatory responses and necrotizing enterocolitis in preterm neonates.
Preterm neonates are susceptible to gastrointestinal disorders such as necrotizing enterocolitis (NEC). Maternal milk and colostrum protects against NEC via growth promoting, immunomodulatory, and antimicrobial factors. The fetal enteral diet amniotic fluid (AF), contains similar components, and we hypothesized that postnatal AF administration reduces inflammatory responses and NEC in preterm n...
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